Oroxylin-A and its phosphonate derivative potentiate eNOS/NO-mediated relaxation and attenuate vasoconstrictor-induced contraction in the mouse aorta

Oroxylin-A (OroA), a flavonoid isolated from Scutellariae baicalensis, alleviates cardiovascular dysfunction. Several procedures for synthesizing OroA have been developed but show low production yield and regioselectivity. We synthesized OroA from baicalin using a one-pot reaction to increase its ov...

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Main Authors: Tzu-Ling Tseng (Author), Wen-Yueh Ho (Author), Po-Jui Huang (Author), Jin-Zhi Liao (Author), Kuan-Han Lee (Author)
Format: Book
Published: Elsevier, 2022-12-01T00:00:00Z.
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