Oroxylin-A and its phosphonate derivative potentiate eNOS/NO-mediated relaxation and attenuate vasoconstrictor-induced contraction in the mouse aorta

• Autores principales: Tzu-Ling Tseng (Autor), Wen-Yueh Ho (Autor), Po-Jui Huang (Autor), Jin-Zhi Liao (Autor), Kuan-Han Lee (Autor)
• Formato: Libro
• Publicado: Elsevier, 2022-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Oroxylin-A (OroA), a flavonoid isolated from Scutellariae baicalensis, alleviates cardiovascular dysfunction. Several procedures for synthesizing OroA have been developed but show low production yield and regioselectivity. We synthesized OroA from baicalin using a one-pot reaction to increase its ov...