The Sigma-2 Receptor Selective Agonist Siramesine (Lu 28-179) Decreases Cocaine-Reinforced Pavlovian Learning and Alters Glutamatergic and Dopaminergic Input to the Striatum

• Hoofdauteurs: Anna M. Klawonn (Auteur), Anna Nilsson (Auteur), Carl F. Rådberg (Auteur), Sarah H. Lindström (Auteur), Mia Ericson (Auteur), Björn Granseth (Auteur), David Engblom (Auteur), Michael Fritz (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Drug addiction is a chronic, debilitating disease that affects millions of people around the world causing a substantial societal burden. Despite decades of research efforts, treatment possibilities remain limited and relapse represents the most treatment-resistant element. Neurosteroid sigma-1 rece...