The Sigma-2 Receptor Selective Agonist Siramesine (Lu 28-179) Decreases Cocaine-Reinforced Pavlovian Learning and Alters Glutamatergic and Dopaminergic Input to the Striatum

• मुख्य लेखकों: Anna M. Klawonn (लेखक), Anna Nilsson (लेखक), Carl F. Rådberg (लेखक), Sarah H. Lindström (लेखक), Mia Ericson (लेखक), Björn Granseth (लेखक), David Engblom (लेखक), Michael Fritz (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Drug addiction is a chronic, debilitating disease that affects millions of people around the world causing a substantial societal burden. Despite decades of research efforts, treatment possibilities remain limited and relapse represents the most treatment-resistant element. Neurosteroid sigma-1 rece...