Exposure of LS-180 Cells to Drugs of Diverse Physicochemical and Therapeutic Properties Up-regulates P-glycoprotein Expression and Activity
Purpose. Drug transporters are increasingly recognized as important determinants of variability in drug disposition and therapeutic response, both in pre-clinical and clinical stages of drug development process. The role P-glycoprotein (P-gp) plays in drug interactions via its inhibition is well est...
Saved in:
Main Authors: | Alaa H Abuznait (Author), Shawn G Patrick (Author), Amal Kaddoumi (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2011-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Inhibitory Activity of Curcumin on P-Glycoprotein and Its Uptake by and Efflux from LS180 Cells Is Not Affected by Its Galenic Formulation
by: Sandra Flory, et al.
Published: (2021) -
Role of Ezrin/Radixin/Moesin in the Surface Localization of Programmed Cell Death Ligand-1 in Human Colon Adenocarcinoma LS180 Cells
by: Takuro Kobori, et al.
Published: (2021) -
Método combinado L.S. 78 THE L.S. 78 COMBINED METHOD
by: Rosa M. Massón Barceló, et al.
Published: (2005) -
Regulation of P-Glycoprotein during Oxidative Stress
by: Aleksey V. Shchulkin, et al.
Published: (2024) -
Characterization of P-Glycoprotein Inhibitors for Evaluating the Effect of P-Glycoprotein on the Intestinal Absorption of Drugs
by: Yusuke Kono, et al.
Published: (2021)