Friend and foe: β-cell Ca2+ signaling and the development of diabetes

Background: The divalent cation Calcium (Ca2+) regulates a wide range of processes in disparate cell types. Within insulin-producing β-cells, increases in cytosolic Ca2+ directly stimulate insulin vesicle exocytosis, but also initiate multiple signaling pathways. Mediated through activation of downs...

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Bibliographic Details
Main Authors: Paul V. Sabatini (Author), Thilo Speckmann (Author), Francis C. Lynn (Author)
Format: Book
Published: Elsevier, 2019-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available