Friend and foe: β-cell Ca2+ signaling and the development of diabetes
Background: The divalent cation Calcium (Ca2+) regulates a wide range of processes in disparate cell types. Within insulin-producing β-cells, increases in cytosolic Ca2+ directly stimulate insulin vesicle exocytosis, but also initiate multiple signaling pathways. Mediated through activation of downs...
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Formaat: | Boek |
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Elsevier,
2019-03-01T00:00:00Z.
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A1234.567 |
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