Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Prif Awduron: Anjong Florence Tikum (Awdur), Anand Krishnan Nambisan (Awdur), Jessica Pougoue Ketchemen (Awdur), Hanan Babeker (Awdur), Musharraf N. Khan (Awdur), Emina E. Torlakovic (Awdur), Humphrey Fonge (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...