Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Hauptverfasser: Anjong Florence Tikum (Verfasst von), Anand Krishnan Nambisan (Verfasst von), Jessica Pougoue Ketchemen (Verfasst von), Hanan Babeker (Verfasst von), Musharraf N. Khan (Verfasst von), Emina E. Torlakovic (Verfasst von), Humphrey Fonge (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-09-01T00:00:00Z.
• Schlagworte: article
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Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...