Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Κύριοι συγγραφείς: Anjong Florence Tikum (Συγγραφέας), Anand Krishnan Nambisan (Συγγραφέας), Jessica Pougoue Ketchemen (Συγγραφέας), Hanan Babeker (Συγγραφέας), Musharraf N. Khan (Συγγραφέας), Emina E. Torlakovic (Συγγραφέας), Humphrey Fonge (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2022-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...