Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Päätekijät: Anjong Florence Tikum (Tekijä), Anand Krishnan Nambisan (Tekijä), Jessica Pougoue Ketchemen (Tekijä), Hanan Babeker (Tekijä), Musharraf N. Khan (Tekijä), Emina E. Torlakovic (Tekijä), Humphrey Fonge (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...