Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Príomhchruthaitheoirí: Anjong Florence Tikum (Údar), Anand Krishnan Nambisan (Údar), Jessica Pougoue Ketchemen (Údar), Hanan Babeker (Údar), Musharraf N. Khan (Údar), Emina E. Torlakovic (Údar), Humphrey Fonge (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2022-09-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...