Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Váldodahkkit: Anjong Florence Tikum (Dahkki), Anand Krishnan Nambisan (Dahkki), Jessica Pougoue Ketchemen (Dahkki), Hanan Babeker (Dahkki), Musharraf N. Khan (Dahkki), Emina E. Torlakovic (Dahkki), Humphrey Fonge (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...