Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Автори: Anjong Florence Tikum (Автор), Anand Krishnan Nambisan (Автор), Jessica Pougoue Ketchemen (Автор), Hanan Babeker (Автор), Musharraf N. Khan (Автор), Emina E. Torlakovic (Автор), Humphrey Fonge (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...