Functionalized Caprolactone-Polyethylene Glycol Based Thermo-Responsive Hydrogels of Silibinin for the Treatment of Malignant Melanoma

• প্রধান লেখক: Behzad Sharif Makhmalzadeh (লেখক), Ommoleila Molavi (লেখক), Mohammad Reza Vakili (লেখক), Hai-Feng Zhang (লেখক), Amir Solimani (লেখক), Hoda Soleymani Abyaneh (লেখক), Raimar Loebenberg (লেখক), Raymond Lai (লেখক), Afsaneh Lavasanifar (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Purpose: Silibinin, is a natural compound, which has shown anticancer activity in various malignancies. In this study, we evaluated the anticancer effects of silibinin in B16-F10 melanoma cells and developed a novel thermoresponsive hydrogel for local delivery of this compound. Method: A thermorespo...