Angiotensin II mediates hypertensive cardiac fibrosis via an Erbb4-IR-dependent mechanism

• Principais autores: Jian-Chun Li (Autor), Jian Jia (Autor), Li Dong (Autor), Zhong-Jing Hu (Autor), Xiao-Ru Huang (Autor), Hong-Lian Wang (Autor), Li Wang (Autor), Si-Jin Yang (Autor), Hui-Yao Lan (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2023-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Transforming growth factor β (TGF-β)/Smad3 plays a vital role in hypertensive cardiac fibrosis. The long non-coding RNA (lncRNA) Erbb4-IR is a novel Smad3-dependent lncRNA that mediates kidney fibrosis. However, the role of Erbb4-IR in hypertensive heart disease remains unexplored and was investigat...