A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer

• 主要な著者: Nora D. Mineva (著者), Stefania Pianetti (著者), Sonia G. Das (著者), Srimathi Srinivasan (著者), Nicolas M. Billiald (著者), Gail E. Sonenshein (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

New targeted treatments are urgently needed to improve triple-negative breast cancer (TNBC) patient survival. Previously, we identified the cell surface protein A Disintegrin And Metalloprotease 8 (ADAM8) as a driver of TNBC tumor growth and spread via its metalloproteinase and disintegrin (MP and D...