A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer

• Main Authors: Nora D. Mineva (Author), Stefania Pianetti (Author), Sonia G. Das (Author), Srimathi Srinivasan (Author), Nicolas M. Billiald (Author), Gail E. Sonenshein (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2024-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

New targeted treatments are urgently needed to improve triple-negative breast cancer (TNBC) patient survival. Previously, we identified the cell surface protein A Disintegrin And Metalloprotease 8 (ADAM8) as a driver of TNBC tumor growth and spread via its metalloproteinase and disintegrin (MP and D...