Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma

• Autori principali: Yongxu Zhou (Autore), Liang Yu (Autore), Peng Huang (Autore), Xudong Zhao (Autore), Risheng He (Autore), Yunfu Cui (Autore), Bo Pan (Autore), Chang Liu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its potential candidate drugs.Methods: We screened afatinib-associat...