Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma

• Main Authors: Yongxu Zhou (Author), Liang Yu (Author), Peng Huang (Author), Xudong Zhao (Author), Risheng He (Author), Yunfu Cui (Author), Bo Pan (Author), Chang Liu (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its potential candidate drugs.Methods: We screened afatinib-associat...