Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma

• Autores principales: Yongxu Zhou (Autor), Liang Yu (Autor), Peng Huang (Autor), Xudong Zhao (Autor), Risheng He (Autor), Yunfu Cui (Autor), Bo Pan (Autor), Chang Liu (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its potential candidate drugs.Methods: We screened afatinib-associat...