Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart

• 主要な著者: Alejandro Lencinas (著者), Danny C. Chhun (著者), Kelvin P. Dan (著者), Kristen D. Ross (著者), Elizabeth A. Hoover (著者), Parker B. Antin (著者), Raymond B. Runyan (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2013-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

SUMMARY Endothelia in the atrioventricular (AV) canal of the developing heart undergo a prototypical epithelial mesenchymal transition (EMT) to begin heart valve formation. Using an in vitro invasion assay, an extracellular matrix protein, Olfactomedin-1 (OLFM1), was found to increase mesenchymal ce...