Evaluation of molecular effects associated with apoptosis, tumour progression, angiogenesis and metastasis by a novel combination of drugs with ormeloxifene in triple negative breast cancer cells

• Egile Nagusiak: Shehna Sharaf (Egilea), Sreelekshmi S (Egilea), Saikant Regidi (Egilea), Abi Santhosh Aprem (Egilea), Rajmohan Gopimohan (Egilea), Lakshmi S (Egilea)
• Formatua: Liburua
• Argitaratua: Open Exploration Publishing Inc., 2024-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Aim: To investigate the molecular effects of a novel combination [sertraline and plumbagin (comb) with ormeloxifene (Orm)] for anticancer activity in triple negative breast cancer cell line "MDA-MB-231". Methods: The cytotoxic effect of the drugs was analyzed by the MTT assay and nuclear m...