Evaluation of molecular effects associated with apoptosis, tumour progression, angiogenesis and metastasis by a novel combination of drugs with ormeloxifene in triple negative breast cancer cells

• Main Authors: Shehna Sharaf (Author), Sreelekshmi S (Author), Saikant Regidi (Author), Abi Santhosh Aprem (Author), Rajmohan Gopimohan (Author), Lakshmi S (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: To investigate the molecular effects of a novel combination [sertraline and plumbagin (comb) with ormeloxifene (Orm)] for anticancer activity in triple negative breast cancer cell line "MDA-MB-231". Methods: The cytotoxic effect of the drugs was analyzed by the MTT assay and nuclear m...