Nonhuman Primates and Humanized Mice for Studies of HIV-1 Integrase Inhibitors: A Review
Since the discovery of the first inhibitors of HIV replication, drug resistance has been a major problem in HIV therapy, due, in part, to the high mutation rate of HIV. Therefore, the development of a predictive animal model is important to identify impending resistance mutations and to possibly inf...
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Case Western Reserve University,
2016-05-01T00:00:00Z.
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