Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses

• 主要な著者: Shuni Duan (著者), Xin Li (著者), Junsong Han (著者), Yang Yang (著者), Ranyi Luo (著者), Yajie Cai (著者), Xiaojiaoyang Li (著者), Qi Zheng (著者), Jincheng Guo (著者), Runping Liu (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Cholangiopathies lack effective medicines and can progress into end-stage liver diseases. Mining natural product transcriptome databases for bioactive ingredients, which can reverse disease-associated transcriptomic phenotypes, holds promise as an effective approach for drug discovery. To identify d...