Selective inhibition of CDK4/6: A safe and effective strategy for developing anticancer drugs

• मुख्य लेखकों: Kai Yuan (लेखक), Xiao Wang (लेखक), Haojie Dong (लेखक), Wenjian Min (लेखक), Haiping Hao (लेखक), Peng Yang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The sustained cell proliferation resulting from dysregulation of the cell cycle and activation of cyclin-dependent kinases (CDKs) is a hallmark of cancer. The inhibition of CDKs is a highly promising and attractive strategy for the development of anticancer drugs. In particular, third-generation CDK...