Synthesis of Celecoxib-Eutectic Mixture Particles via Supercritical CO₂ Process and Celecoxib Immediate Release Tablet Formulation by Quality by Design Approach

• প্রধান লেখক: Seung-Hyeon Hong (লেখক), Linh Dinh (লেখক), Sharif Md Abuzar (লেখক), Eun Seok Lee (লেখক), Sung-Joo Hwang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Significant improvements in the wettability and dissolution rate of celecoxib (CEL), a poorly soluble selective cyclooxygenase-2 (COX-2) inhibitor, have been shown by Huyn et al., 2019 by combining the binary pharmaceutical compositions including CEL and one of the two co-formers, adipic acid (ADI)...