5-HT1F Receptor Agonist Ameliorates Mechanical Allodynia in Neuropathic Pain via Induction of Mitochondrial Biogenesis and Suppression of Neuroinflammation

• Автори: Long-Qing Zhang (Автор), Ya-Qun Zhou (Автор), Jia-Yan Li (Автор), Jia Sun (Автор), Shuang Zhang (Автор), Jia-Yi Wu (Автор), Shao-Jie Gao (Автор), Xue-Bi Tian (Автор), Wei Mei (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Neuropathic pain is a devastating disease that affects millions of people worldwide. Serotonin (5-hydroxytryptamine, 5-HT) is involved in pain modulation. Several lines of evidence have indicated that 5-HT1F receptor agonists are potent inducers of mitochondrial biogenesis. In this study, we tested...