Integrating network pharmacology, molecular docking and experimental verification to reveal the mechanism of artesunate in inhibiting choroidal melanoma

• Main Authors: Qing-yue Ma (Author), Yi-chong Liu (Author), Qian Zhang (Author), Wen-dan Yi (Author), Ying Sun (Author), Xiao-di Gao (Author), Xin-tong Zhao (Author), Hao-wen Wang (Author), Ke Lei (Author), Wen-juan Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundArtesunate (ART), a natural compound derived from Artemisia annua, has shown promising clinical potentials in the treatment of various tumors, but the exact mechanism is unclear. Choroidal melanoma (CM) is a major malignant ocular tumor in adults, known for its significant malignancy and p...