Integrating network pharmacology, molecular docking and experimental verification to reveal the mechanism of artesunate in inhibiting choroidal melanoma

• Hoofdauteurs: Qing-yue Ma (Auteur), Yi-chong Liu (Auteur), Qian Zhang (Auteur), Wen-dan Yi (Auteur), Ying Sun (Auteur), Xiao-di Gao (Auteur), Xin-tong Zhao (Auteur), Hao-wen Wang (Auteur), Ke Lei (Auteur), Wen-juan Luo (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

BackgroundArtesunate (ART), a natural compound derived from Artemisia annua, has shown promising clinical potentials in the treatment of various tumors, but the exact mechanism is unclear. Choroidal melanoma (CM) is a major malignant ocular tumor in adults, known for its significant malignancy and p...