Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

• Главные авторы: Jingwen Dong (Автор), Chenfei Zhu (Автор), Ying Huang (Автор), Quanhao Li (Автор), Jing Li (Автор), Zheng Wang (Автор), Yixin Wang (Автор), Zhanwei Zhou (Автор), Minjie Sun (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2023-07-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Fibrosis is one of the key factors that lead to the immune exclusion of solid tumors. Although degradation of fiber is a promising strategy, its application was still bottlenecked by the side effects of causing metastasis, resulting in the failure of immunotherapy. Here, we developed an antimetastat...