Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

• Päätekijät: Jingwen Dong (Tekijä), Chenfei Zhu (Tekijä), Ying Huang (Tekijä), Quanhao Li (Tekijä), Jing Li (Tekijä), Zheng Wang (Tekijä), Yixin Wang (Tekijä), Zhanwei Zhou (Tekijä), Minjie Sun (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2023-07-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Fibrosis is one of the key factors that lead to the immune exclusion of solid tumors. Although degradation of fiber is a promising strategy, its application was still bottlenecked by the side effects of causing metastasis, resulting in the failure of immunotherapy. Here, we developed an antimetastat...