Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion.

• Main Authors: Stephen M Christensen (Author), Laura A L Dillon (Author), Lucas P Carvalho (Author), Sara Passos (Author), Fernanda O Novais (Author), V Keith Hughitt (Author), Daniel P Beiting (Author), Edgar M Carvalho (Author), Phillip Scott (Author), Najib M El-Sayed (Author), David M Mosser (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patients with late cutaneous leishmaniasis. Although para...