Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion.

• Autores principales: Stephen M Christensen (Autor), Laura A L Dillon (Autor), Lucas P Carvalho (Autor), Sara Passos (Autor), Fernanda O Novais (Autor), V Keith Hughitt (Autor), Daniel P Beiting (Autor), Edgar M Carvalho (Autor), Phillip Scott (Autor), Najib M El-Sayed (Autor), David M Mosser (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patients with late cutaneous leishmaniasis. Although para...