Limited Associations Between 5-HT Receptor Gene Polymorphisms and Treatment Response in Antidepressant Treatment-Free Patients With Depression

• Principais autores: Taichi Ochi (Autor), Natalya M. Vyalova (Autor), Innokentiy S. Losenkov (Autor), Diana Z. Paderina (Autor), Ivan V. Pozhidaev (Autor), Anton J. M. Loonen (Autor), German G. Simutkin (Autor), Nikolay A. Bokhan (Autor), Svetlana A. Ivanova (Autor), Bob Wilffert (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Major depressive disorder has become a prominent cause of disability, as lifetime prevalence has increased to ~15% in the Western world. Pharmacological effects of serotonin (5-hydroxytryptamine, 5-HT) are mediated through 5-hydroxytryptamine receptor (5-HTR) binding. Serotonin regulation of amygdal...