Limited Associations Between 5-HT Receptor Gene Polymorphisms and Treatment Response in Antidepressant Treatment-Free Patients With Depression

• প্রধান লেখক: Taichi Ochi (লেখক), Natalya M. Vyalova (লেখক), Innokentiy S. Losenkov (লেখক), Diana Z. Paderina (লেখক), Ivan V. Pozhidaev (লেখক), Anton J. M. Loonen (লেখক), German G. Simutkin (লেখক), Nikolay A. Bokhan (লেখক), Svetlana A. Ivanova (লেখক), Bob Wilffert (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Major depressive disorder has become a prominent cause of disability, as lifetime prevalence has increased to ~15% in the Western world. Pharmacological effects of serotonin (5-hydroxytryptamine, 5-HT) are mediated through 5-hydroxytryptamine receptor (5-HTR) binding. Serotonin regulation of amygdal...