Onchocerciasis Drug Discovery: In Vitro Evaluation of FDA-Approved Drugs against <i>Onchocerca gutturosa</i> in Gambia

• Główni autorzy: Suzanne Gokool (Autor), Simon Townson (Autor), Andrew Freeman (Autor), Jadzia Siemienski-Kleyn (Autor), Jakub Zubrzycki (Autor), Senyo Tagboto (Autor), Marc P. Hübner (Autor), Ivan Scandale (Autor)
• Format: Książka
• Wydane: MDPI AG, 2024-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Onchocerciasis treatment and control relies mainly on the use of ivermectin which has high activity against the microfilarial stage of <i>Onchocerca volvulus</i> but limited activity against the long-lived, tissue dwelling adult nematodes. As this neglected tropical disease has now been...