Comparison of an Addictive Potential of μ-Opioid Receptor Agonists with G Protein Bias: Behavioral and Molecular Modeling Studies

Among different approaches to the search for novel-safer and less addictive-opioid analgesics, biased agonism has received the most attention in recent years. Some μ-opioid receptor agonists with G protein bias, including SR compounds, were proposed to induce diminished side effects. However, in man...

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Main Authors: Lucja Kudla (Author), Ryszard Bugno (Author), Sabina Podlewska (Author), Lukasz Szumiec (Author), Lucja Wiktorowska (Author), Andrzej J. Bojarski (Author), Ryszard Przewlocki (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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