Multi-Target Inhibitor CUDC-101 Impairs DNA Damage Repair and Enhances Radiation Response in Triple-Negative Breast Cell Line

• Главные авторы: Elsie Neo Seane (Автор), Shankari Nair (Автор), Charlot Vandevoorde (Автор), Alessandra Bisio (Автор), Anna Joubert (Автор)
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• Опубликовано: MDPI AG, 2024-11-01T00:00:00Z.
• Предметы: article
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Background: Since the discovery that Histone deacetylase inhibitors (HDCAi) could enhance radiation response, a number of HDACi, mainly pan-HDAC inhibitors, have been studied either as monotherapy or in combination with X-ray irradiation or chemotherapeutic drugs in the management of breast cancer....