Multi-Target Inhibitor CUDC-101 Impairs DNA Damage Repair and Enhances Radiation Response in Triple-Negative Breast Cell Line

Background: Since the discovery that Histone deacetylase inhibitors (HDCAi) could enhance radiation response, a number of HDACi, mainly pan-HDAC inhibitors, have been studied either as monotherapy or in combination with X-ray irradiation or chemotherapeutic drugs in the management of breast cancer....

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Hoofdauteurs: Elsie Neo Seane (Auteur), Shankari Nair (Auteur), Charlot Vandevoorde (Auteur), Alessandra Bisio (Auteur), Anna Joubert (Auteur)
Formaat: Boek
Gepubliceerd in: MDPI AG, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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