Early-Life Stress Induces Depression-Like Behavior and Synaptic-Plasticity Changes in a Maternal Separation Rat Model: Gender Difference and Metabolomics Study

• 主要な著者: Yongfei Cui (著者), Kerun Cao (著者), Huiyuan Lin (著者), Sainan Cui (著者), Chongkun Shen (著者), Wenhao Wen (著者), Haixin Mo (著者), Zhaoyang Dong (著者), Shasha Bai (著者), Lei Yang (著者), Yafei Shi (著者), Rong Zhang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

More than 300 million people suffer from depressive disorders globally. People under early-life stress (ELS) are reportedly vulnerable to depression in their adulthood, and synaptic plasticity can be the molecular mechanism underlying such depression. Herein, we simulated ELS by using a maternal sep...