Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the <i>Substantia Nigra</i> of Male Rodents and Primary Mesencephalic Cultures

The tissue renin-angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson's disease (PD). We studied the activation of the NLRP3 inflammasome in the <i>sub...

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Main Authors: Aloia Quijano (Author), Carmen Diaz-Ruiz (Author), Andrea Lopez-Lopez (Author), Begoña Villar-Cheda (Author), Ana Muñoz (Author), Ana I. Rodriguez-Perez (Author), Jose L. Labandeira-Garcia (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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