Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the <i>Substantia Nigra</i> of Male Rodents and Primary Mesencephalic Cultures
The tissue renin-angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson's disease (PD). We studied the activation of the NLRP3 inflammasome in the <i>sub...
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MDPI AG,
2022-02-01T00:00:00Z.
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