Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the <i>Substantia Nigra</i> of Male Rodents and Primary Mesencephalic Cultures

• Auteurs principaux: Aloia Quijano (Auteur), Carmen Diaz-Ruiz (Auteur), Andrea Lopez-Lopez (Auteur), Begoña Villar-Cheda (Auteur), Ana Muñoz (Auteur), Ana I. Rodriguez-Perez (Auteur), Jose L. Labandeira-Garcia (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The tissue renin-angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson's disease (PD). We studied the activation of the NLRP3 inflammasome in the <i>sub...