Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the <i>Substantia Nigra</i> of Male Rodents and Primary Mesencephalic Cultures

• প্রধান লেখক: Aloia Quijano (লেখক), Carmen Diaz-Ruiz (লেখক), Andrea Lopez-Lopez (লেখক), Begoña Villar-Cheda (লেখক), Ana Muñoz (লেখক), Ana I. Rodriguez-Perez (লেখক), Jose L. Labandeira-Garcia (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The tissue renin-angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson's disease (PD). We studied the activation of the NLRP3 inflammasome in the <i>sub...