Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay

• Main Authors: Niusha Sharifi (Author), Khosro Khajeh (Author), Shabnam Mahernia (Author), Saeed Balalaie (Author), Ghasem Ataie (Author), Raheleh Jahanbani (Author), Massoud Amanlou (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Somatic ACE is a two-domain protein, C and N which are resulted from gene duplication. Presence of two active sites with particular properties, demonstrates functional significance of each domain. Increased levels of circulating N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), could be t...