Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay

• Glavni autori: Niusha Sharifi (Autor), Khosro Khajeh (Autor), Shabnam Mahernia (Autor), Saeed Balalaie (Autor), Ghasem Ataie (Autor), Raheleh Jahanbani (Autor), Massoud Amanlou (Autor)
• Format: Knjiga
• Izdano: Tabriz University of Medical Sciences, 2018-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Background: Somatic ACE is a two-domain protein, C and N which are resulted from gene duplication. Presence of two active sites with particular properties, demonstrates functional significance of each domain. Increased levels of circulating N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), could be t...