Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications

• Main Authors: Tatjana Michel (Author), Daniel Luft (Author), Meike-Kristin Abraham (Author), Sabrina Reinhardt (Author), Martha L. Salinas Medina (Author), Julia Kurz (Author), Martin Schaller (Author), Meltem Avci-Adali (Author), Christian Schlensak (Author), Karlheinz Peter (Author), Hans Peter Wendel (Author), Xiaowei Wang (Author), Stefanie Krajewski (Author)
• Format: Book
• Published: Elsevier, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Synthetically modified mRNA is a unique bioactive agent, ideal for use in therapeutic applications, such as cancer vaccination or treatment of single-gene disorders. In order to facilitate mRNA transfections for future therapeutic applications, there is a need for the delivery system to achieve opti...