Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications

• Главные авторы: Tatjana Michel (Автор), Daniel Luft (Автор), Meike-Kristin Abraham (Автор), Sabrina Reinhardt (Автор), Martha L. Salinas Medina (Автор), Julia Kurz (Автор), Martin Schaller (Автор), Meltem Avci-Adali (Автор), Christian Schlensak (Автор), Karlheinz Peter (Автор), Hans Peter Wendel (Автор), Xiaowei Wang (Автор), Stefanie Krajewski (Автор)
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• Опубликовано: Elsevier, 2017-09-01T00:00:00Z.
• Предметы: article
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Synthetically modified mRNA is a unique bioactive agent, ideal for use in therapeutic applications, such as cancer vaccination or treatment of single-gene disorders. In order to facilitate mRNA transfections for future therapeutic applications, there is a need for the delivery system to achieve opti...