EM-transcriptomic signature predicts drug response in advanced stages of high-grade serous ovarian carcinoma based on ascites-derived primary cultures

• 主要な著者: Diana-Roxana Constantinescu (著者), Andrei Sorop (著者), Alina-Veronica Ghionescu (著者), Daniela Lixandru (著者), Vlad Herlea (著者), Nicolae Bacalbasa (著者), Simona Olimpia Dima (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: High-grade serous ovarian carcinoma (HGSOC) remains a medical challenge despite considerable improvements in the treatment. Unfortunately, over 75% of patients have already metastasized at the time of diagnosis. Advances in understanding the mechanisms underlying how ascites cause chem...