EM-transcriptomic signature predicts drug response in advanced stages of high-grade serous ovarian carcinoma based on ascites-derived primary cultures

• Главные авторы: Diana-Roxana Constantinescu (Автор), Andrei Sorop (Автор), Alina-Veronica Ghionescu (Автор), Daniela Lixandru (Автор), Vlad Herlea (Автор), Nicolae Bacalbasa (Автор), Simona Olimpia Dima (Автор)
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• Опубликовано: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Предметы: article
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Introduction: High-grade serous ovarian carcinoma (HGSOC) remains a medical challenge despite considerable improvements in the treatment. Unfortunately, over 75% of patients have already metastasized at the time of diagnosis. Advances in understanding the mechanisms underlying how ascites cause chem...