EM-transcriptomic signature predicts drug response in advanced stages of high-grade serous ovarian carcinoma based on ascites-derived primary cultures

• Prif Awduron: Diana-Roxana Constantinescu (Awdur), Andrei Sorop (Awdur), Alina-Veronica Ghionescu (Awdur), Daniela Lixandru (Awdur), Vlad Herlea (Awdur), Nicolae Bacalbasa (Awdur), Simona Olimpia Dima (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Introduction: High-grade serous ovarian carcinoma (HGSOC) remains a medical challenge despite considerable improvements in the treatment. Unfortunately, over 75% of patients have already metastasized at the time of diagnosis. Advances in understanding the mechanisms underlying how ascites cause chem...