Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction

• Главные авторы: Tingjuan Ni (Автор), Na Lin (Автор), Xingxiao Huang (Автор), Wenqiang Lu (Автор), Zhenzhu Sun (Автор), Jie Zhang (Автор), Hui Lin (Автор), Jufang Chi (Автор), Hangyuan Guo (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Предметы: article
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Myocardial contractile dysfunction in diabetic cardiomyocytes is a significant promoter of heart failure. Herein, we investigated the effect of icariin, a flavonoid monomer isolated from Epimedium, on diabetic cardiomyopathy (DCM) and explored the mechanisms underlying its unique pharmacological car...